Lansoprazole vs. Omeprazole

Lansoprazole is a proton pump inhibitor that is generally used to treat GERD or gastro-esophageal reflux diseases. The disease mainly occurs when the acid in the stomach tries to move up and eventually cause the heartburn and even damage of the esophagus. . Lansoprazole is also prescribed for the treatments of ulcers and to prevent ulcers in patients whose ulcers have had it earlier.  Zollinger-Ellison syndrome or production of more acid by stomach is also taken care of by lansoprazole.

On the other hand, omeprazole is also a proton pump inhibitor and is used for the ailment of peptic ulcers, GERD and Zollinger-Ellison syndrome like the lansoprazole.  Both Lansoprazole and the omeprazole are combined with other medicines to treat Helicobacter pylori. Omeprazole is combined with amoxillin and clarithromycin. Thus, Lansoprazole vs Omeprazole means to compare the efficiency of lansoprazole and omeprazole in the eradication of the gastro-esophageal reflux diseases. This is mainly measured by the esophageal pH monitoring system.

In general the lansoprazole side effects as well as omeprazole are dizziness, insomnia, blistering pain, rashes, diarrhea, nausea, abdominal pain etc. but the side effects lead to by the omeprazole is experienced only by 1% of the total people who intake the drug. On the other hand, the adverse effects of lansoprazole are very frequent for the people over 50 years who take the medicine.

To judge Lansoprazole vs Omeprazole there is a method. Say 70 patients who are suffering from gastro esophageal reflux diseases are chosen randomly. At first, some of them are given 20 mg. omeprazole and the others are given 30 mg. lansoprazole. After three weeks or four weeks of the start of the treatment, the patients are taken for oesophageal pH monitoring. However, in most of the cases the results remain abnormal. Then the dosage of the proton pump inhibitor is doubled and the patient is again taken through the 24-h pH-metry after 30 days.

Now, if 35 patients were taking omeprazole and the rest lansoprazole then, 29% of the omeprazole takers are treated with 30 mg. of lansoprazole daily for the next 30 days and 68% of the lansoprazole takers are prescribed with the 20 mg. omeprazole for the next 30 days. In all the above medications, that is after double dosage of the proton pump inhibitors gives normal results.

Now, in the Lansoprazole vs Omeprazole, both of the medicines are highly prescribed and available in the market. However, for the normalization and the ailment of the gastro esophageal reflux diseases and to stop the upcoming of the acid in the stomach, the lansoprazole shows more efficacy than the omeprazole. Moreover drug interactions of lansoprazoles are less compared to that of omeprazoles. Nevertheless, both the medicines are well prescribed depending on the sensitivity of the patients towards

the adverse effects of the medicines. It is to mention here, that for large gastric ulcers and syndromes, omeprazoles are more effective than the lansoprazole. So, it is always advised to consult the physicians well, before you start the dosage of both the proton pump inhibitors.

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